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Crystal structure of the nucleosome core particle at 16 Å resolution

Graham A. Bentley, Anita Lewit-Bentley, John T. Finch, Alberto D. Podjarny, M. Roth

Journal:

Journal of Molecular Biology

Année:

1984

Langue:

english

Fichier:

PDF, 2.06 MB

english, 1984

Ultrahigh resolution drug design I: Details of interactions in human aldose reductase–inhibitor complex at 0.66 Å

E.I. Howard, R. Sanishvili, R.E. Cachau, A. Mitschler, B. Chevrier, P. Barth, V. Lamour, M. Van Zandt, E. Sibley, C. Bon, D. Moras, T.R. Schneider, A. Joachimiak, A. Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 577 KB

english, 2004

When this means that: The role of working memory and inhibitory control in children’s understanding of representations

Astle, Andrea, Kamawar, Deepthi, Vendetti, Corrie, Podjarny, Gal

Journal:

Journal of Experimental Child Psychology

Année:

2013

Langue:

english

Fichier:

PDF, 781 KB

english, 2013

A multicopy modeling of the water distribution in macromolecular crystals

Alberto D. Podjarny, Eduardo I. Howard, Alexander Urzhumtsev, J. Raul Grigera

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1997

Langue:

english

Fichier:

PDF, 250 KB

english, 1997

Aldose and aldehyde reductases: Correlation of molecular modeling and mass spectrometric studies on the binding of inhibitors to the active site

Ossama El-Kabbani, Hélène Rogniaux, Patrick Barth, Roland P.-T. Chung, Elisabeth V. Fletcher, Alain Van Dorsselaer, Alberto Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2000

Langue:

english

Fichier:

PDF, 407 KB

english, 2000

Protein Crystallography at Subatomic Resolution

T. Petrova, A. Podjarny

Journal:

ChemInform

Année:

2005

Fichier:

PDF, 8 KB

2005

High-resolution crystallography and drug design

R. E. Cachau, A. D. Podjarny

Journal:

Journal of Molecular Recognition

Année:

2005

Langue:

english

Fichier:

PDF, 153 KB

english, 2005

Probing the ultra-high resolution structure of aldose reductase with molecular modelling and noncovalent mass spectrometry

Connie Darmanin, Guillaume Chevreux, Noelle Potier, Alain Van Dorsselaer, Isabelle Hazemann, Alberto Podjarny, Ossama El-Kabbani

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 652 KB

english, 2004

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications

Michael C. Van Zandt, Evelyn O. Sibley, Erin E. McCann, Kerry J. Combs, Brenda Flam, Diane R. Sawicki, Al Sabetta, Anne Carrington, Janet Sredy, Eduardo Howard, Andre Mitschler, Alberto D. Podjarny

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 436 KB

english, 2004

Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications

Michael C. Van Zandt, Brian Doan, Diane R. Sawicki, Janet Sredy, Alberto D. Podjarny

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 378 KB

english, 2009

Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies

H Rogniaux, A Van Dorsselaer, P Barth, J.F Biellmann, J Barbanton, M van Zandt, B Chevrier, E Howard, A Mitschler, N Potier, L Urzhumtseva, D Moras, A Podjarny

Journal:

Journal of the American Society for Mass Spectrometry

Année:

1999

Langue:

english

Fichier:

PDF, 523 KB

english, 1999

Structure of human aldose reductase holoenzyme in complex with Statil: An approach to structure-based inhibitor design of the enzyme

Ossama El-Kabbani, Paul Ramsland, Connie Darmanin, Roland P.-T. Chung, Alberto Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2003

Langue:

english

Fichier:

PDF, 511 KB

english, 2003

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

Ossama El-Kabbani, Connie Darmanin, Thomas R. Schneider, Isabelle Hazemann, Federico Ruiz, Mitsuru Oka, Andrzejj Joachimiak, Clemens Schulze-Briese, Takashi Tomizaki, Andre Mitschler, Alberto Podjarny

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 482 KB

english, 2004

Virtual screening for inhibitors of human aldose reductase

Oliver Kraemer, Isabelle Hazemann, Alberto D. Podjarny, Gerhard Klebe

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2004

Langue:

english

Fichier:

PDF, 361 KB

english, 2004

Frontier example in experimental charge density research: Experimental electrostatics of proteins

C. Lecomte, B. Guillot, C. Jelsch, A. Podjarny

Journal:

International Journal of Quantum Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 698 KB

english, 2005

Molecular dynamics simulation of crystal water with X-ray constraints

J. Raul Grigera, Tomas S. Grigera, Eduardo I. Howard, Alberto Podjarny

Journal:

International Journal of Quantum Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 387 KB

english, 1994

Structural analysis of denaturant-protein interactions: Comparison between the effects of bromoethanol and SDS on denaturation and renaturation of triclinic lysozyme

Ada Yonath, Alberto Podjarny, Barry Honig, Wolfie Traub, Anita Sielecki, Osnat Herzberg, John Moult

Journal:

European Biophysics Journal

Année:

1978

Langue:

english

Fichier:

PDF, 502 KB

english, 1978

Role of glomerular prostanoid in control of glomerular filtration rate in rats

J. Bernheim, E. Podjarny, A. Pomeranz, M. Rathaus

Journal:

Journal of Molecular Medicine

Année:

1988

Langue:

english

Fichier:

PDF, 634 KB

english, 1988

Subatomic and atomic crystallographic studies of aldose reductase: implications for inhibitor binding

A. Podjarny, R.E. Cachau, T. Schneider, M. Van Zandt, A. Joachimiak

Journal:

Cellular and Molecular Life Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 552 KB

english, 2004

Introduction

A. Podjarny

Journal:

Cellular and Molecular Life Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 61 KB

english, 2004

Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites

O. El-Kabbani, A. Podjarny

Journal:

Cellular and Molecular Life Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 561 KB

english, 2007

Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase–inhibitor complex

M. P. Blakeley, A. Mitschler, I. Hazemann, F. Meilleur, D. A. A. Myles, A. Podjarny

Journal:

European Biophysics Journal

Année:

2006

Langue:

english

Fichier:

PDF, 521 KB

english, 2006

Crystal structure of a eukaryotic initiator tRNA

SCHEVITZ, RICHARD W., PODJARNY, ALBERTO D., KRISHNAMACHARI, N., HUGHES, JOHN J., SIGLER, PAUL B., SUSSMAN, JOEL L.

Journal:

Nature

Année:

1979

Fichier:

PDF, 618 KB

1979

High resolution structure of the RNA duplex [U(U-A)6A]2

Dock-Bregeon, A. C., Chevrier, B., Podjarny, A., Moras, D., deBear, J. S., Gough, G. R., Gilham, P. T., Johnson, J. E.

Journal:

Nature

Année:

1988

Fichier:

PDF, 631 KB

1988

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

Rondeau, J.-M., Tête-Favier, F., Podjarny, A, Reymann, J.-M., Barth, P., Biellmann, J.-F., Moras, D.

Journal:

Nature

Année:

1992

Fichier:

PDF, 490 KB

1992

Hypercalcemic nephropathy: Chronic disease with predominant medullary inner stripe injury

Rosen, Seymour, Greenfeld, Zev, Bernheim, Jacques, Rathaus, Mauro, Podjarny, Eduardo, Brezis, Mayer

Journal:

Kidney International

Année:

1990

Langue:

english

Fichier:

PDF, 1.66 MB

english, 1990

Glomeruli cooperate with macrophages in converting arachidonic acid to prostaglandins and hydroxyeicosatetraenoic acids

Josée Sraer, Laurent Baud, Marcelle Bens, Eduardo Podjarny, Detlef Schlondorff, Raymond Ardaillou, Jean-Daniel Sraer

Journal:

Prostaglandins, Leukotrienes and Medicine

Année:

1984

Langue:

english

Fichier:

PDF, 488 KB

english, 1984

Effect of potassium loading on prostaglandin E2 and F2α excretion in the brattleboro rat

M. Rathaus, N. Kariv, J. Shapira, E. Podjarny, J. Bernheim

Journal:

Prostaglandins, Leukotrienes and Medicine

Année:

1985

Langue:

english

Fichier:

PDF, 354 KB

english, 1985

Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders

Gabrielle Zeder-Lutz, Laurence Choulier, Marie Besse, Alexandra Cousido-Siah, Francesc Xavier Ruiz Figueras, Bruno Didier, Marie-Louise Jung, Alberto Podjarny, Danièle Altschuh

Journal:

Analytical Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2012

Metabolic regulation of the squid nerve Na+/Ca2+ exchanger: Recent kinetic, biochemical and structural developments

Graciela Berberián, Alberto Podjarny, Reinaldo DiPolo, Luis Beaugé

Journal:

Progress in Biophysics and Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2012

Neutron crystallography: opportunities, challenges, and limitations

Matthew P Blakeley, Paul Langan, Nobuo Niimura, Alberto Podjarny

Journal:

Current Opinion in Structural Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1021 KB

english, 2008

Animal models of preeclampsia

Eduardo Podjarny, Chris Baylis, Gyorgy Losonczy

Journal:

Seminars in Perinatology

Année:

1999

Langue:

english

Fichier:

PDF, 1.21 MB

english, 1999

A ‘specificity’ pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil

A Urzhumtsev, F Tête-Favier, A Mitschler, J Barbanton, P Barth, L Urzhumtseva, J-F Biellmann, AD Podjarny, D Moras

Journal:

Structure

Année:

1997

Langue:

english

Fichier:

PDF, 983 KB

english, 1997

NADH-dependent prostaglandin E2-9-ketoreductase activity and prostaglandin synthesis in the Brattleboro rat kidney: effects of the antidiuretic hormone

M. Rathaus, M.M. Werber, E. Podjarny, N. Kariv, J. Bernheim

Journal:

Clinica Chimica Acta

Année:

1986

Langue:

english

Fichier:

PDF, 443 KB

english, 1986

High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase

Tobias Marquardt, Dirk Kostrewa, Rajkumar Balakrishnan, Antonietta Gasperina, Christian Kambach, Alberto Podjarny, Fritz K. Winkler, Ganesaratnam K. Balendiran, Xiao-Dan Li

Journal:

Journal of Molecular Biology

Année:

2005

Langue:

english

Fichier:

PDF, 945 KB

english, 2005

High-resolution Crystal Structure of Aldose Reductase Complexed with the Novel Sulfonyl-pyridazinone Inhibitor Exhibiting an Alternative Active Site Anchoring Group

Holger Steuber, Matthias Zentgraf, Alberto Podjarny, Andreas Heine, Gerhard Klebe

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 507 KB

english, 2006

Merging the Binding Sites of Aldose and Aldehyde Reductase for Detection of Inhibitor Selectivity-determining Features

Holger Steuber, Andreas Heine, Alberto Podjarny, Gerhard Klebe

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 5.76 MB

english, 2008

X-Ray-Radiation-Induced Cooperative Atomic Movements in Protein

Tatiana Petrova, Vladimir Y. Lunin, Stephan Ginell, Isabelle Hazemann, Krzysztof Lazarski, André Mitschler, Alberto Podjarny, Andrzej Joachimiak

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 829 KB

english, 2009

Chronic exogenous hyperinsulinemia (CHI) in pregnancy: A rat model of pregnancy induced hypertension (PIH)

M. Bursztyn, E. Podjarny, J. Bernheim

Journal:

American Journal of Hypertension

Année:

1997

Langue:

english

Fichier:

PDF, 106 KB

english, 1997

The structure of triclinic lysozyme at 2·5 Å resolution

J. Moult, A. Yonath, W. Traub, A. Smilansky, A. Podjarny, D. Rabinovich, A. Saya

Journal:

Journal of Molecular Biology

Année:

1976

Langue:

english

Fichier:

PDF, 1005 KB

english, 1976

Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex

Petrova, Tatiana, Steuber, Holger, Hazemann, Isabelle, Cousido-Siah, Alexandra, Mitschler, Andre, Chung, Roland, Oka, Mitsuru, Klebe, Gerhard, El-Kabbani, Ossama, Joachimiak, Andrzej, Podjarny, Albert

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 254 KB

english, 2005

Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat: Implications for Inhibitor Binding and Selectivity

El-Kabbani, Ossama, Carbone, Vincenzo, Darmanin, Connie, Oka, Mitsuru, Mitschler, Andre, Podjarny, Alberto, Schulze-Briese, Clemens, Chung, Roland P.-T.

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 285 KB

english, 2005

Protein crystallography at subatomic resolution

Petrova, T, Podjarny, A

Journal:

Reports on Progress in Physics

Année:

2004

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2004

Effect of sodium and chloride depletion on urinary prostaglandin F2α excretion in potassium loaded rats

Rathaus, M., Bernheim, J., Katz, D., Green, J., Podjarny, E.

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Année:

1992

Langue:

english

Fichier:

PDF, 617 KB

english, 1992

HOTEL-DIEU.

Podjarny, Eduardo, Losonczy, Gyorgy, Baylis, Chris

Journal:

The Lancet

Année:

1828

Langue:

english

Fichier:

PDF, 206 KB

english, 1828

Animal models of preeclampsia

Podjarny, Eduardo, Losonczy, Gyorgy, Baylis, Chris

Journal:

Seminars in Nephrology

Année:

2004

Langue:

english

Fichier:

PDF, 281 KB

english, 2004

Author index

Podjarny, Eduardo, Losonczy, Gyorgy, Baylis, Chris

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Année:

1972

Langue:

english

Fichier:

PDF, 111 KB

english, 1972

Crystallographic structure of an RNA helix: [U(UA)6A]2

Dock-Bregeon, A.C., Chevrier, B., Podjarny, A., Johnson, J., de Bear, J.S., Gough, G.R., Gilham, P.T., Moras, D.

Journal:

Journal of Molecular Biology

Année:

1989

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1989

Sodium loading and renal prostaglandins in old rats

Rathaus, M., Greenfeld, Z., Podjarny, E., Brezis, M., Bernheim, J.

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Année:

1993

Langue:

english

Fichier:

PDF, 562 KB

english, 1993

Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family

Roman, Ernesto A., Faraj, Santiago E., Cousido-Siah, Alexandra, Mitschler, André, Podjarny, Alberto, Santos, Javier

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2013

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2013